Losing weight following type 2 diabetes diagnosis boosts chance of remission

People who lose at least 10% of their body weight in the first year after being diagnosed with type 2 diabetes increase their chances of being in remission after five years, compared with those whose weight remains stable. Losing this achievable amount of weight over the next four years also makes remission more likely | Via National Institute for Health Research 


In this study of 867 people, 257 (30%) achieved remission at five-year follow-up. The participants had been taking part in a trial but had not received intensive lifestyle interventions or been put on extremely calorie-restricted diets.

This NIHR-funded study strengthens the evidence that healthy behaviour change and weight loss can result in remission of type 2 diabetes. This finding may help to motivate people to lose weight soon after a diabetes diagnosis ─ setting realistic and achievable targets can make a difference in the longer term.

Further detail at National Institute for Health research

Full reference: Dambha‐Miller H, Day AJ, Strelitz J et al. | Behaviour change, weight loss and remission of Type 2 diabetes: a community‐based prospective cohort study | Diabetic Medicine

Diabetes UK strategy 2020-2025

Diabetes UK has launched a new strategy called ‘A generation to end the harm: Diabetes UK Strategy 2020-2025’ coinciding with World Diabetes Day 2019 

Image source: https://www.diabetes.org.uk/

There are an estimated 2.85 million people diagnosed with type 2 diabetes in England, and more than 850,000 living with the condition who do not know they have it because they have not yet been diagnosed − bringing the total up to 3.7 million.

The new strategy from Diabetes UK focuses on achieving five key outcomes by 2025:

  • more people with type 1, type 2 and all other forms of diabetes will benefit from new treatments that cure or prevent the condition
  • more people will be in remission from type 2 diabetes
  • more people will get the quality of care they need to manage their diabetes well
  • fewer people will get type 2 and gestational diabetes
  • more people will live better and more confident lives with diabetes, free from discrimination.

The charity said that more than half of all cases of type 2 diabetes could be prevented or delayed, and in turn, the risk of developing the related complications, by tackling overweight and obesity.

Full document: A generation to end the harm: Diabetes UK Strategy 2020-2025

See also: Obesity rate doubles over past 20 years | OnMedica

Breast, cervical and colorectal cancer screening in adults with diabetes: a systematic review and meta-analysis

Bhatia, D., Lega, I. C., Wu, W., & Lipscombe, L. L. |2019| Breast, cervical and colorectal cancer screening in adults with diabetes: a systematic review and meta-analysis| Diabetologia| 1-15.

Individuals  with diabetes are at an increased risk of developing cancer.A new study published in the journal Diabetologica has quantified an association between association between diabetes and participation in breast, cervical and colorectal cancer screening.




Individuals with diabetes are at increased risk of developing and dying from cancer. Evidence-based guidelines recommend universal screening for breast, cervical and colorectal cancer; however, evidence on the uptake of these tests in individuals with diabetes is mixed. We conducted a meta-analysis to quantify the association between diabetes and participation in breast, cervical and colorectal cancer screening.



MEDLINE, EMBASE and CINAHL were searched systematically for publications between 1 January 1997 and 18 July 2018. The search was supplemented by handsearching of reference lists of the included studies and known literature reviews. Abstracts and full texts were assessed in duplicate according to the following eligibility criteria: study conducted in the general population; diabetes included as a predictor vs a comparison group without diabetes; and breast (mammography), cervical (Papanicolaou smear) or colorectal (faecal and endoscopic tests) cancer screening uptake included as an outcome. Random-effects meta-analyses were performed using the most-adjusted estimates for each cancer site.



Thirty-seven studies (25 cross-sectional, 12 cohorts) were included, with 27 studies on breast, 19 on cervical and 18 on colorectal cancer screening. Having diabetes was associated with significantly lower likelihood of breast and cervical  cancer screening, relative to not having diabetes. Colorectal cancer screening was comparable across groups with and without diabetes ; however, women with diabetes were less likely to receive a colorectal cancer screening test than women without diabetes.



Our findings suggest that women with diabetes have suboptimal breast, cervical and colorectal cancer screening rates, compared with women without diabetes, although the absolute differences might be modest. Given the increased risk of cancer in this population, higher quality prospective evidence is necessary to evaluate the contribution of diabetes to cancer screening disparities in relation to other patient-, provider- and system-level factors. (Source: Bhatia, Lega, Wu & Lipscombe, 2019)

If you are Rotherham NHS staff and interested in reading the full article, why not request it from the Library ?

In the news:

Diabetes.co.uk Cancer screening rates lower among women with diabetes

Flash: My diabetes crystal ball

NHS England | November 2019 | Flash: My diabetes crystal ball

To mark Diabetes Awareness month this month (November) NHS England are publishing a series of blogs from the perspective of patients with diabetes. In the first blog, a patient with type 1 diabetes explains how using flash glucose monitoring has been life-changing in managing her condition.

Flash: My diabetes crystal ball