New-Onset Type 1 Diabetes in Children During COVID-19: Multicenter Regional Findings in the U.K.

Unsworth, R. et al. (2020) |New-Onset Type 1 Diabetes in Children During COVID-19: Multicenter Regional Findings in the U.K.| Diabetes Care |https://doi.org/10.2337/dc20-1551

The authors of this report used patient information a multicenter regional data from North West London (NWL) of newonset type 1 diabetes and diabetic ketoacidosis (DKA) in children up to the age of 16 years during the peak of the COVID19 pandemic. they collected data from five inpatient units (four National Health Service [NHS] Trusts) comprising the NWL Pediatric Diabetes Network between 23 March (coinciding with the commencement of the U.K. Government lockdown) and 4 June. Thirty children aged 23 months to 16.8 years presented with new-onset type 1 diabetes.

To the best of their knowledge, this is the first report to describe an apparent increase in new-onset type 1 diabetes in children during the COVID-19 pandemic,
with evidence of SARS-CoV-2 infection or exposure in a proportion of those tested.
The authors’ intention is to raise awareness of a possible link between SARS-CoV-2 and
new-onset type 1 diabetes, especially as there are reports of incident type 1 diabetes
occurring as apparently small localized outbreaks. Further studies are required to establish a definitive link and any possible impact on the severity of type 1 diabetes
presentation, including severe hypokalemia.

Full article available from Diabetes Care